The young persons guide to conquering (and saving) the world. Prescribing of Newer Diabetes Drugs Not Up to Snuff in Black Patients? Once you stop taking it, however, you may return to your baseline weight and blood-sugar levels. For some, Ozempic is contraindicated: Its not advised for anyone pregnant or breastfeeding or with a personal or family history of medullary thyroid carcinoma or multiple endocrine tumors. Doctors who understand the physiology of the drug and have the time to follow up with patients regularly and appropriately should be the only doctors who prescribe the drug, says Dr. Rahmana. Thats because many of these drugs are stimulants. 28 Feb 2023 22:31:15 anticonvulsants such as phenytoin. If youre going to take an antihypertensive medication, it will lower your blood pressure but only while youre taking it. Kenzi Abou-Sabe is a reporter and producer in the NBC News Investigative Unit. Oh, oh, oh, Ozempic, croon the voices in an oft-aired commercial for the Type 2 diabetes drug, Ozempic by Novo Nordisk. Side effects of Tagamet (cimetidine) can include headache, dizziness, drowsiness, and diarrhea. Low blood sugar (hypoglycemia) can make you feel very hungry, dizzy, irritable, or shaky. ( TRULICITY), and semaglutide (OZEMPIC) compare with placebo. Ozempic belongs to the glucagon-like peptide-1 agonist class of medications (GLP-1). Ozempic was approved by the FDA in 2017 and patients taking the drug for up totwo years were included in safety trials. Wilding, J., Batterham, R. L., Calanna, S., et al. Follow your doctor's dosing instructions very carefully. When you have AFib, youll need to take blood thinners like warfarin (coumadin) to lower your odds for blood clots and stroke. Both groups showed a decrease in alcohol consumption, but patients diagnosed with obesity who were treated with the GLP-1 compound and therapy dramatically reduced the amount they drank, compared with those who only received the placebo and therapy. Sorry, we have no data available. He also emphasizes breathwork, biofeedback, stress management, and sleep, which he believes are beneficial for bolstering and maintaining a healthy diet. Overdose may cause severe nausea, vomiting, or low blood sugar. Novo Nordisk Announces FDA Approval of Label Update for Rybelsus (semaglutide) Allowing Use as a First-Line Option for Adults with Type 2 Diabetes. Sometimes the foods we eat and the beverages we drink can also interact with our medications. Ozempic and Wegovy are injected under the skin, usually once per week at any time of the day, with or without food. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. There are so many pieces of treatment, including addressing any sleep disorders. It is a once-weekly prescription According to Antonio Ciaccia, its a problem for brand-name drugs in general. 0 mg in patients with type 2 diabetes (SUSTAIN FORTE): a double-blind, randomised, phase 3B trial. If you develop persistent, severe, abdominal pain, which may radiate to the back or be accompanied by vomiting, ring your doctor immediately as Ozempic can increase your risk of developing pancreatitis. Do not use two doses of semaglutide at one time. Society seems to have a generational trend cycle when it comes to weight loss and appearance politics. The change, he said, was needed to keep his pharmacy afloat. This includes certain staple pain relievers like ibuprofen and aspirin. If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. What conditions does Ozempic Pen Injector treat? Hux is among a group of independent pharmacists who have stopped carrying Ozempic and other drugs in the same class, in part, they say, because of the underpayments by pharmacy benefits managers, who act as middlemen between pharmacists and insurers. If you have a fast heart rate because of a medication, you also may feel: Whatever you think the reason may be, if you find it difficult to breathe or the chest pain lasts more than a few minutes, call 911 or go to the nearest hospital. Similarly, with obesity, when youre taking an anti-obesity medication, youre able to change your physiology a little bit, but it only works while youre on the medication. Dr. Hu added that thinking of a medicine like semaglutide purely as a weight-loss medication can also be problematic. There are some clues: Semaglutide belongs to a class of drugs called glucagon-like peptide 1 receptor agonists, which mimic a hormone in our bodies that makes us feel full. However, limiting alcoholic, greasy, sugary foods/drinks, as well as refined carbohydrates, may be more beneficial. Ozempic may temporarily worsen diabetic retinopathy, an eye condition. Teen Vogue covers the latest in celebrity news, politics, fashion, beauty, wellness, lifestyle, and entertainment. Store Rybelsus in the original package at room temperature, away from moisture and heat. Your doctor will tell you how long to take moxifloxacin. For an optimal experience visit our site on another browser. Scientists are working to understand why people like Ms. Zarpour experience this side effect. Ozempic treats patients who have diabetes, therefore it is meant to be taken indefinitely, says Dr. Rahnama. If your next dose is due in less than 2 days (48 hours), skip the missed dose and return to your regular schedule. Ozempic is not for treatment of type 1 diabetes mellitus. arrow-right. Tenpas said Ozempic and Wegovy are FDA-approved for the treatment of type 2 diabetes, obesity and prevention of cardiovascular disease, but prescribers can also prescribe them for off-label uses, including nonalcoholic steatohepatitis. antidepressants such as tricyclic antidepressants (such as amitriptyline and nortriptyline) or monoamine oxidase inhibitors (MAOI) (eg, selegiline, isocarboxazid, and phenelzine), beta-blockers, such as atenolol, labetalol, and metoprolol, may enhance the hypoglycemic effects, corticosteroids, such as prednisone or cortisone, diuretics, such as bumetanide, HCTZ, and bendroflumethiazide, HIV medications, such as amprenavir, atazanavir, and fosamprenavir, hormones, such as ethinylestradiol and hydroxyprogesterone, insulin (may increase the risk of hypoglycemia). While some on social media seem to be promoting the belief that you need only one miracle drug to lose weight, these medications are meant to be part of a broad-based strategy. Follow all directions on your prescription label and read all medication guides or instruction sheets. Ozempic Injection: A Warning You Shouldnt Ignore! Medically reviewed by Carmen Fookes, BPharm. Its been studied and indicated for people with either type 2 diabetes or the medical problem of overweight and/or obesity.. Together with metformin, Ozempic effectively manages blood sugar levels to treat type 2 diabetes. Insulin secretion typically occurs in two phases following a meal, and Ozempic increased both first and second-phase insulin secretion. ONeil, P. M., Birkenfeld, A. L., McGowan, B., et al. Further, this off-label use of Ozempic is greatly impacting the availability of the medication for those who need it most., Beyond the physical impact,Janet Lydecker, PhD, an assistant professor of psychiatry at the Yale School of Medicine, noted that if people experience quick weight loss, it can lead to more weight bias and disordered eating. Use the medicine exactly as directed. Wegovy marked the beginning of a new generation of anti-obesity medications that were highly effective, says Dr. Butsch. Diabetic Retinopathy Complications. WebThe choice of medications should be based on efficacy, risk of weight gain, hypoglycemia and cardiovascular and renal safety of available drugs. Theme: News Way by Themeansar. Yes. For Wegovy: Use the medicine as soon as you can and then go back to your regular schedule. Wegovy was approved in 2021 and studied in four separate 68-week studies. Swallow the tablet whole and do not crush, chew, or break it. The medication also makes your body more sensitive to the insulin that you produce on your own, adds Holly Lofton, MD, a clinical associate professor in the departments of surgery and medicine and director of the Medical Weight Management Program at NYU Langone Health. She would try to have a drink but struggled to finish. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 15 Things To Know About Your Menstrual Cycle, Young People With Long COVID Share Their Experiences, 2023 Cond Nast. Ozempic should not be used in people with a history of thyroid cancer or those with Multiple Endocrine Neoplasia syndrome type 2. arrow-right. Obesity, says Dr. Butsch, is often thought of as a lifestyle choice with medications acting as so-called management tools. Studies have found that an oral anticoagulant that you take by mouth is better at preventing blood clots than an aspirin. As a subscriber, you have 10 gift articles to give each month. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. Its use for quick weight loss is just another tool in the same diet culture that has been pervasive for prettymuch all of the 20th and 21st centuries and doesnt seem to be going away anytime soon. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. Latest news in the world of drugs, supplements & trending health. It should not make you feel that way, adds Dr. Lofton, explaining that anyone in that situation should have discontinued use, had their dose dramatically lowered, and/or had an evaluation sonogram. When blood glucose levels increase, albiglutide assists the pancreas in releasing insulin. Do not inject into the same place two times in a row. Do not use past the expiration date. Side effects of Tagamet (cimetidine) can include headache, dizziness, drowsiness, and diarrhea. Examples of these include: banaba Some independent pharmacies have made the decision to not stock pricey brand-name drugs, including Ozempic. Selected from data included with permission and copyrighted by First Databank, Inc. You're going to have less of a successful management plan if youre ignoring key pieces that relate to your physiology.. A shortage of Ozempic. Semaglutide (Ozempic/Rybelsus) is a GLP-1 receptor agonist that helps improve blood sugar control by stimulating insulin release, slowing gastric emptying, and WebHIV antivirals for example abacavir, didanosine, emtricitabine, lamivudine, stavudine, tenofovir alafenamide and disoproxil fumarate as well as zidovudine. Bruce Willis Has a Rare Form of Dementia, Family Announces, Potential Male Birth Control Pill Shows Promise in Early Lab Tests, Instagram Live: Hollywood's Newest Weight-Loss Drug, 3 in 4 teens lost weight in obesity drug trial, Diabetes drug in low supply amid TikTok weight loss trend, A personal mission to get obese patients on GLP-1 agonists, A Deeper Look at Hollywood's Newest Weight Loss Drug, New generation of weight loss medications offer promise but at a price, How an overreliance on BMI can stand between patients and treatment. Hausner, H., Derving Karsbl, J., Holst, A. G., et al. Sincalide: Sulfonylureas: Thiazide and Thiazide-Like Diuretics : Ozempic and herbs and supplements Taking certain herbs or supplements with Ozempic might increase the risk of hypoglycemia (low blood sugar levels). He was seeing reimbursements at about $10 to $40 below the cost of the drugs. Even during a birthday lunch, the type of social event where she would typically enjoy a cocktail or two, she couldnt bring herself to drink. But these drugs also act as blood thinners. multiple endocrine neoplasia type 2 (tumors in your glands); or. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. He was seeing Within the first six months of Wegovy being introduced as a treatment for obesity in July 2021, there were supply shortages due to both demand and factory production, says Dr. Butsch, which led many to use Ozempic in its place. WebStimulant medications. antidepressants such as tricyclic Severe side effects are rare but include depression, nervousness, and hallucination. To revist this article, visit My Profile, then View saved stories. Can You Take Benadryl and Tylenol Together? A special diet for semaglutide doesn't exist. Semaglutide increasesinsulin release in response to glucose intake and causes a minor delay in gastric emptying, says Ariana Chao, MD, an assistant professor at the University of Pennsylvania School of Nursing and medical director of the schools Center for Weight and Eating Disorders. This feeling of tiredness may come on suddenly or gradually develop. As Ozempic gains more attention and morepeople use the diabetes drug off-label to lose weight, doctors say that many patients are reporting similar experiences: They start the medication and then stop wanting to drink alcohol. Ozempic has not been adequately studied in pregnant women and should not be used unless the perceived benefits outweigh the risks of uncontrolled diabetes, which include preeclampsia, spontaneous abortions, and preterm delivery. If pancreatitis is confirmed, the patient should not take Ozempic. Last month Elon Musk credited Wegovy, a similar drug, as one of the reasons for his more svelte appearance (fasting was the other); Andy Cohen tweeted about #Ozempic in September, a hashtag that has clocked over 274 million views on TikTok; and its been widely suggested that Kim Kardashian relied on the drug for dramatic weight loss in pursuit of fitting intoMarilyn Monroes famous wiggle dress at this years Met Gala. Effectiveness of metformin on weight loss in non-diabetic individuals with obesity. He had expected his eating habits to change once he began taking the medication he became less interested in fatty, sugary foods and found himself eating smaller meals but he didnt anticipate the aversion to alcohol. Paige TwenterAfter taking an obesity drug each week for more than a year, 73 percent of teenage study participants recorded a weight loss of at least 5 percent. Separating Fact From Fiction. Throw away an injection pen that has been frozen. This is why nutritionists, such as Charles Passler, DC, underscore the simultaneous importance of nutrition choices and lifestyle while on the drug. He doesnt think his decision not to carry the drugs has led to lost business. Semaglutide (Rybelsus and Ozempic) is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus (not for type 1 diabetes). Cerner Multum provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. Experts do not recommend it for cosmetic weight loss. If you also need to self-administer insulin, administer the insulin at a different site to the Ozempic, at least 15cm apart. Protect from heat and light. You have a known allergic reaction to semaglutide (the active ingredient in Wegovy or Ozempic). In the simplest terms, it curbs the appetite and tricks the body into feeling full. Theyre take it or leave it. Insulin Secretagogue (Sulfonylurea and Glinides), Glyburide (Glynase PresTab, Diabeta), and, Adverse GI events like diarrhea, vomiting, renal (kidneys) dysfunction, and dehydration, Diabetic ketoacidosis (DKA, diabetic acidosis), Multiple Endocrine Neoplasia Syndrome Type 2 (MEN2), Hypersensitivity to semaglutide or any of the other components of Ozempic, Inadequate glycemic control despite diet and exercise (semaglutide is not recommended as a first-line of therapy). Monotherapy failure For patients with deterioration of glycemic management while taking initial oral monotherapy, many available medication classes can be used with metformin or in combination with each other if metformin is Ozempic was rumored to be the secret behind several recent celebrity weight-loss transformations, and TikTok videos featuring creators talking about and taking Ozempic havemillions of views, with even more comments from users asking how to get their hands on the drug. If needed, you may store an unopened Wegovy pen at cool room temperature for up to 28 days. Taking Ozempic with insulin (as well as other medications such as sulfonylureas that also lower blood sugar levels) increases your risk of hypoglycemia (low blood sugar levels) so monitor yourself for symptoms of low blood sugar which include sweating, shaking, dizziness, a fast heartbeat, and mood changes. Using BMI as a determining factor for who qualifies poses its own issues as well. Nonsteroidal anti-inflammatory drugs (NSAIDs). eye problems caused by diabetes (retinopathy). The latest fashion news, beauty coverage, celebrity style, fashion week updates, culture reviews, and videos on Vogue.com. Christine MeyerObesity is not the consequence of bad behaviors it is a disease that finally has effective, safe, lasting treatments. Whats it like taking Ozempic? Nate Hux, the owner of Pickerington Pharmacy in Ohio, stopped stocking the diabetes drug which has soared in popularity, particularly for its off-label use as a weight loss aid last summer. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Doing so with early puberty is even harder. Ask your doctor for a safer medicine to use during this time. You should refer to the prescribing information for Ozempic for a complete list of interactions. A higher 2 mg dose was approved in early 2022, says W. Scott Butsch, MD, MSc, director of obesity medicine in the Bariatric and Metabolic Institute at Cleveland Clinic. Research suggests high doses of omega-3 fatty acids could increase the risk of developing AFib. But taking medications for off-label use can be risky. We see such drastic attempts to lose weight because the pressure is so strong This could lead to major consequences with weight-loss medications that might not be appropriate for teens, said Dr. Lydecker. But we seem to be back to the beginning again. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. This raises thyroxine (T4) hormones in your body. Those promoting Ozempic for cosmetic weight loss claim that it offers a fast, no-frills option for slimming down. That, however, has left many who need the drug to manage diabetes at a loss. Your provider can guide you on how to schedule your medications. I just wasnt expecting it, she said of her new distastefor alcohol. Immune modulators for example immune globulins, immunosuppressive agents and immunostimulants, for example bacterial and viral vaccines. warfarin (Jantoven) If your thyroid, a butterfly-shaped gland at the base of your neck, doesnt make enough hormones that your body needs, you have hypothyroidism. unusual mood changes, thoughts about hurting yourself; pounding heartbeats or fluttering in your chest; a light-headed feeling, like you might pass out; low blood sugar (in people with type 2 diabetes); upset stomach, heartburn, burping, gas, bloating; nausea, vomiting, stomach pain, loss of appetite. Mounjaro, metformin, simvastatin, Xarelto, Jardiance, Trulicity, phentermine, semaglutide, Wegovy, Lantus. The shortages impact both drugs, and some people who may have been prescribed Wegovy for weight loss weretaking Ozempic, according to NBC News. All rights reserved. All rights reserved. 3 Tagamet can increase the side effects of statins. All rights reserved. Ozempic does not take the place of insulin and is not effective in people with type 1 diabetes or for the treatment of diabetic ketoacidosis. 3 Tagamet can increase the side effects of statins. You either accept the contract or you lose access to patients.. All rights reserved. For Rybelsus: Skip the missed dose and use your next dose at the regular time. More research is needed to determine how medications like Ozempic affect alcohol consumption, but scientists say they are encouraged by the findings so far. Finding a low price for brand-name drugs, however, is much harder, because they are sold by a single manufacturer and are usually offered to pharmacists at a set price, he said. Onestudy found that the majority of peoplegained back most of the weight they lost while using semaglutide one year after stopping the medication. Mental health concerns need to be addressed and any disordered eating needs to be addressed. Ozempic belongs to the class of medicines called GLP-1 receptor agonists. Semaglutide mimics the actions of GLP-1, a naturally occurring hormone that helps to regulate blood glucose levels. The development adds a twist to the Ozempic saga in the U.S., where many patients over the last year have been forced to visit multiple pharmacies in search of the drug, which has been difficult to find because of shortages. craftsman Every time you take it, you get that full feeling for six or seven days, and that will compound over time. Like any other prescription medication, Ozempic has potential side effects, largelyincluding gastrointestinal issues. Stimulant medications. WebRT @grumpycubau: Its fascinating how quickly the discourse around ozempic started sounding like the discourse around HRT. For more information, please visit our page on Ozempic and alcohol interactions. Ozempic may cause serious side effects, including: Possible thyroid tumors, including cancer. Get emergency medical help if you have signs of an allergic reaction: hives, itching; dizziness, fast heartbeats; difficult breathing; swelling of your face, lips, tongue, or throat. But when used inappropriately, an appetite can be completely suppressed, which can lead to or worsen eating disorders. When weight loss occurs for appearance, for power, for popularity, for happiness, thats when westart to see some of those diet-culture trends and disordered eating.. Ozempic was approved by the FDA in 2017 and patients taking the drug for up to two years were included in safety trials. Youre supposed to add it on to lifestyle modifications just as you would in hypertension or in type 2 diabetes, she told Teen Vogue. WebSerious Interactions. It may be used as a monotherapy (alone) or with other medicines for the same. Patients share their stories. Methyldopa is in a class of medications called antihypertensives. As the diabetes drug gains more attention, a surprising side effect has emerged. Ozempic belongs to a class of drugs called Antidiabetics, Glucagon-like Peptide-1 Agonists. Nausea and vomiting, constipation, and loose stools are widely reported and, for some, lead to the discontinuation of the drug. These medications may interact and cause very harmful effects. Currently, theres not much information on which oral drugs Ozempic may interact with. The reimbursement rates offered by pharmacy benefit managers are meant to incentivize pharmacists to shop around for the lowest-priced drug, Ciaccia said. Separating Fact from Fiction, Black Seed Oil Uses, Benefits, and Side Effects. Tell your doctor if you inadvertently become pregnant while taking Ozempic. Danil Nevsky/Stocksy. Also, because Ozempic causes a delay in gastric emptying, it may impact the absorption of any medication taken orally. No particular foods should be strictly avoided while using Ozempic. Tell your doctor if you notice any change in your vision. Underpayments are a huge problem for independent pharmacists, who are often given lower reimbursement rates than larger retail pharmacy chains that have more bargaining power, said Inma Hernandez, an associate professor at the University of California, San Diegos Skaggs School of Pharmacy and Pharmaceutical Sciences. No particular foods should be strictly avoided while using Ozempic. Report any symptoms of a possible thyroid tumor (such as a lump in the neck, shortness of breath, difficulty swallowing, or persistent hoarseness) to your doctor immediately. (Anew paper demonstrates its safety and efficacy in adolescents as well.) As the diabetes drug gains more attention, a surprising side effect has emerged. DrugGenius225 S. Mermac AveUnit 832TClayton, MO 63131. Ask a doctor if it is safe to breastfeed while using Ozempic or Wegovy. If you or your child has attention deficit hyperactivity disorder (ADHD), your doctor will give you stimulant drugs such as methylphenidate to control your symptoms. Is Avocado Oil A Seed Oil? According to the FDA, people with a family history of medullary thyroid cancer or patients with a rare disorder called multiple endocrine neoplasia type 2 syndrome should not use Ozempic. Taking certain herbs or supplements with Ozempic might increase the risk of hypoglycemia (low blood sugar levels). 2023 Cond Nast. Oh, oh, oh, Ozempic, croon the voices in an oft-aired commercial for the Type 2 diabetes drug, Ozempic by Novo Nordisk. The list below covers all groups of drugs that can negatively interact with CBD oil. Anaphylaxis and angioedema have also been reported with GLP-1 RAs and the initial administration of Ozempic should preferably be done in a medical facility. Also, it may lower the risks of These are newer medications, so we dont have long-term outcome studies, especially in young people and pediatric patients, Michelle Van Name, MD, an assistant professor in pediatric endocrinology and diabetes at Yale School of Medicine, toldTeen Vogue. Patients with obesity have been marginalized long enough. For some medications, you might have to be cautious about how much of it you can take safely. Ask your doctor or nurse to show you how to self-administer Ozempic before you first do it yourself. Select a condition to view a list of medication options. No one should be injecting diabetes medication to lose weight! You should not breastfeed while using Rybelsus. No particular foods should be strictly avoided while using Ozempic. If someone just wants to drop a few pounds, I mean, come on, this is not appropriate for them, says Dr. Passler. Ozempic was approved by the FDA in 2017 and patients taking the drug for up to two years were included in safety trials. Its certainly something Ive heard many of my patients say, usually in a positive way, said Dr. Robert Gabbay, the chief scientific and medical officer of the American Diabetes Association. Available for Android and iOS devices. Angiotension II Blockers Antiarrhythmics Antibiotics Antidepressants Anticonvulsants / Anti-Seizure Medications Antihistamines Antipsychotics Anesthetics Beta-Blockers Benzodiazepines Calcium Channel Blockers HIV Antivirals HMG CoA Ozempic may also be given to reduce the risk of future cardiovascular events, such as a heart attack or stroke, in people with type 2 diabetes who also have heart disease. You should not breastfeed while using Rybelsus. Tanzeum (Albiglutide) Tanzeum is a weekly injectable that comes in a pre-filled pen. Place it in a puncture-proof "sharps" container and dispose of it following state or local laws. UseOzempic (Subcutaneous)exactly as directed on the label, or as prescribed by your doctor. When naturally produced, the hormone [that Ozempic mimics] only keeps us full for a couple of hours, whereas in medication form, fullness is appreciated for 24 hours, says Dr. Rahnama. Some people taking Ozempic have reported feeling less excited or, in some cases, even disgusted by the foods they once enjoyed. J. Paul Grayson, a 73-year-old in Clayton, Okla., used to keep a six-pack of beer tucked in the back of his fridge. The results were published Nov. 2 in The New England Journal of Medicine. If you have heart problems, check with your doctor before you start taking antibiotics. Ozempic Drug Interactions: What Medications Should Be Avoided? Julie ApplebyRepurposed diabetes drugs offer a new option to help with weight loss. I have patients telling me they can eat a third of what they normally ate and be satiated, go longer without eating, and dont snack anymore, says Dr. Lofton. With acombination of fenfluramine or dexfenfluramine (appetite suppressants) and phentermine (an amphetamine), demand for the drug soared and many doctors doled out prescriptions. I cant afford to give away things anymore just out of kindness and goodwill, Hoffart said. A semaglutide, which is the active ingredient in Ozempic, belongs to a class of medications called GLP-1 agonists.

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